ncRNA name | H-Ras siRNA |
ncRNA Category | siRNA |
Disease name | diabetic retinopathy (DR) |
Species | Bos taurus |
Tissues/Cell_line | bovine retinal endothelial cells (BRECs) |
Methods | siRNA transfection, Western blot, qRT-PCR, semi-qPCR, ELISA |
Expression pattern | associated |
Functional description | Membrane translocation of H-Ras is a plausible mechanism responsible for accelerated apoptosis of retinal capillary cells in diabetes. H-Ras-siRNA prevented this translocation, and also decreased their apoptosis. |
PubMed ID | 19607814 |
Year | 2009 |
Title | Translocation of H-Ras and its implications in the development of diabetic retinopathy. |
Drug-related ncRNA | NO |
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